Profile of L-type Ca2+ current and Na+/Ca2+ exchange current during cardiac action potential in ventricular myocytes
نویسندگان
چکیده
منابع مشابه
Profile of L-type Ca(2+) current and Na(+)/Ca(2+) exchange current during cardiac action potential in ventricular myocytes.
OBJECTIVE The L-type Ca(2+) current (I(Ca,L)) and the Na(+)/Ca(2+) exchange current (I(NCX)) are major inward currents that shape the cardiac action potential (AP). Previously, the profile of these currents during the AP was determined from voltage-clamp experiments that used Ca(2+) buffer. In this study, we aimed to obtain direct experimental measurement of these currents during cardiac AP wit...
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2012
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2011.08.029